When you align objects in design studio you must be aware the anchoring can change.
After aligning objects the anchor is set to the same side you made the alignment.
There are 2 red objects in a yellow panel they are not aligned and you want to align them to the right side, like this:
A very simple task, often used when working on the layout of a dashboard. But with this simple task a major layout flaw might have entered your dashboard. Before the aligning the 2 objects where anchored at the left side, like this:
After selecting both and aligning them to the right, both anchors have changed to the right side, like this:
So if the yellow panel is changing size, both of your red objects re-position in a different way.